Friday, July 24, 2009

Since triple-negative breast cancer is not fueled by hormones, is it safe for a triple-negative survivor to become pregnant after treatment or could i

I agree with everything Dr. Dupree mentioned. I approach things slightly differently in my clinic. The first question I think we need to ask is whether a pregnancy subsequent to breast cancer diagnosis increases the risk of recurrence of that cancer. While it is very difficult to say for certain, such evidence as we have suggests that there is not likely to be a major increase in risk of recurrence. The second question is a much more difficult one to my mind, and that is to say should a patient become pregnant knowing that it is possible that the child she brings into this world may grow up without a mother? This gets to the question of risk of recurrence, and in particular the risk of the recurrence that a woman would have with or without a pregnancy. As Dr. Dupree mentioned, one of the reasons for waiting for a pregnancy, especially in triple-negative breast cancer survivors, is that the greatest risk of recurrence in triple-negative breast cancer occurs relatively early on, in the first few years after diagnosis. Other factors that help determine the risk of recurrence are classic factors such as tumor size and number of lymph nodes involved. The patient and her spouse therefore need to consider what degree of risk they are willing to accept prior to a patient becoming pregnant. This is often one of the more difficult discussions that families and physicians can ever have, but certainly a very important one.

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